原作者： Semhar Tewelde，肖鋒譯 文章來源： 中華急診醫學雜志編輯部 發布日期：2013-04-22
Title: HIV and Coronary Heart Disease (CHD)
題目：艾滋病與冠狀動脈心臟病（CHD）
Author 作者: Semhar Tewelde
HIV infected patients are at higher calculated risk for CHD compared w/the general population of the same age
與一般同年齡人相比，艾滋病毒感染者患冠心病的風險性較高
HIV is known to promote atherosclerosis through mechanisms related to immune activation, chronic inflammation, coagulation disorders, and lipid disturbances
艾滋病毒是通過相關的免疫激活，慢性炎癥，凝血功能障礙，和血脂紊亂機制，促進動脈粥樣硬化形成
Additionally combination anti-retroviral therapy (cART) has an affect on lipid and glucose metabolism demonstrated both in vitro and in vivo
此外，體內和體外試驗都證實了聯合抗逆轉錄病毒療法（cART）對脂質和葡萄糖代謝的影響
The presence of an accelerated process of coronary atherosclerosis in this population is a major concern
這一人群中，冠狀動脈粥樣硬化進程的加快是一個相當大的問題
Practitioners should have a high index of suspicion when confronted by young HIV patients and further data/strategies to prevent early CHD in HIV-infected patients is warranted
醫護人員在治療年輕的艾滋病患者時應該有一個高度的警覺性，一定要形成一個以防止艾滋病患者發生早期冠心病的方案
References 參考文獻：
Boccara F, et al. HIV and Coronary Heart Disease. J Am Coll Cardiol 2013;61:511–23
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