原作者： 肖鋒（Feng Xiao） 文章來源： 中華急診醫學雜志編輯部 發布日期：2013-05-11
Title: B-Type Natriuretic Peptide
題目：B型利鈉肽
Author 作者: Semhar Tewelde
B-type natriuretic peptide (BNP) is a useful prognostic biomarker in patients with reduced LVEF, but data in heart failure (HF) with preserved ejection fraction (HFPEF) is minimal
B型利鈉肽（BNP）對有左室功能減低的心衰患者是一個可靠的判斷預后的生物指標，但對左室射血分數正常的心力衰竭（HFPEF）病人的數據卻非常有限。
A recent study sought to determine the prognostic value of BNP in patients with HFPEF in comparison to data in HF patients with reduced left ventricular EF <40%
最近的一項研究評估了BNP對HFPEF患者的預后價值，并與左室EF<40％的心衰患者的數據進行了比較
615 patients with mild to moderate HF were followed for 18 months and BNP was measured at baseline and related to the primary outcomes (mortality and HF hospitalization)
615例輕度至中度心衰患者在測量了BNP水平后隨訪了18個月，觀察了BNP與主要指標 （死亡率和心衰住院率）的關系
BNP levels were significantly higher in patients with reduced LVEF than in those with HFPEF (p < 0.001), however the risk of adverse outcomes and prognosis in patients with HFPEF is as poor as in those with reduced LVEF
左室EF降低患者的BNP水平明顯高于那些HFPEF病人（P <0.001），但是HFPEF患者的預后和那些左室EF降低的病人一樣不佳
References 參考文獻：
B-Type Natriuretic Peptide and Prognosis in Heart Failure Patients With Preserved and Reduced Ejection Fraction. Veldhuisen D, Linssen G, et al. J Am Coll Cardiol 2013; 61:1498-506
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